Necator sp. (L3) larva.
Hookworm ova are collected from a known source regularly tested for Hepatitis A/B/C, HIV 1/o/2, CMV and Strongyloides by an independent laboratory. The collected ova are washed in an anti-microbial agent, and then incubated to their infectious stage in soil bacteria fortified growth medium. The infectious larva (L3) are treated with an anti-microbial agent and put into a buffer solution.
The L3 are placed on the skin where they begin their transpulmonary migration to the intestinal tract. In two to three weeks the worms will undergo their final molt and reside in the intestinal tract. Once in the intestinal tract the worms will interact with the intestinal mucosa and modulate the immune system.
Use of Hookworm based on Theory
The conditions that are actively being researched are Crohn's Disease, Ulcerative Colitis, Asthma, Allergies, Coeliac disease, Eczema, Multiple Sclerosis, and Psoriasis. There are theoretical reasons to believe that Atherosclerosis, Depression, Eosinophilic esophagitis , Grave's disease, Irritable bowel syndrome, Fibromyalgia, Hashimoto's thyroiditis, Sjorgen's syndrome, Lupus, Migraine, Peyronies Disease , Rheumatoid Arthritis, Psoriasic Arthritis and Diabetes type I might respond.
Side Effects and Warning for Human Hookworm
Light hookworm infection is often asymptomatic or has mild-to-moderate complaints. The most common reactions are a pruritic papulovesicular rash may develop at the site of larval penetration (ground itch) and fatigue. Migration larvae though the lungs occasionally causes a cough. During the acute phase, adult worms in the intestine may cause colicky epigastric pain, night sweats, fever, anorexia, flatulence, diarrhea and weight loss or weight gain. Eosiniophilic enteritis is also common. A low-grade eosinophilia is often present. There have been reported cases of reactive arthritis that resolved with treatment.
Trichuris sp. ova
Whipworm ova are collected from a known source regularly tested for Hepatitis A/B/C, HIV 1/o/2, and CMV by an independent laboratory. The collected ova are washed in an anti-microbial agent, and then incubated to their infectious stage in soil derived growth medium. The infectious ova are treated with an anti-microbial modality and put into a buffer solution.
The ova are ingested. Once in the small intestines the worms molt and migrate to the large intestines. Adult whipworms invade the intestinal mucosa and modulate the immune system.
Use of Whipworm based on Theory
Crohn's and Ulcerative Colitis
Side Effects and Warnings for Human Whipworm
Light infections are frequently asymptomatic or have mild-to-moderate complaints. Common symptoms include intermittent abdominal pain, fever, headache and diarrhea. Less common are reports of vomiting. A low-grade eosinophilia may be present. There are reports of vitamin A deficiency in chronic infections. Intestinal bleeding and anemia are a rare but reported side effect.
Combination therapy consists of different intestinal worms. Each helminth works in a unique region of the gastrointestinal tract. The worms are introduced in a specific schedule; the principle being, not to over-populate an already treated region of the intestinal mucosa, but to combine therapeutic benefit from multiple regions. This therapy requires sixteen-twenty months to reach complete dosing and a minimum of two trips to our clinic in Mexico.
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